Non-Hodgkin's Lymphoma Classification and a Case Review

Bashar Dabbas, M.D., provides an overview of lymphoma classifications and strategies for effective diagnosis.

Click here for a 7-minute slide presentation with audio
(please allow up to 60 seconds for download)

Educational Objectives
After viewing this program, participants will be able to:

• Discuss the applicability of the WHO and REAL lymphoma classifications
• Relate the NCCN guidelines to the diagnosis for non-Hodgkin's lymphoma
• Understand the significance of correlating technologies (Morphology, Cytogenetics/FISH, Flow) for an accurate diagnosis, even in difficult situations such as dry taps

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TCR-Beta PCR Provides Greater Specificity and
Sensitivity for Detecting Malignant Lymphomas

TCR-Beta rather than Gamma chain assessment provides¹:
--Increased specificity
--Increased sensitivity

TCR-Beta facilitates²:
--Determination of the lineage of leukemias and lymphomas
--Monitoring of disease recurrence
--Detection of residual disease

Genoptix uses the BIOMED-2 standardized reagents and methods as recently published in Leukemia for:
--T-cell Clonality Assessment by TCR-Beta PCR
--B-cell Clonality Assessment by IgH PCR

This optimal protocol detects clonality in 94% of T-cell malignancies and 99% of B-cell malignancies¹.

Comprehensive Assessments (COMPASS™) for Lymphomas
A complete COMPASS work-up for suspected lymphomas includes, as medically necessary:

• Reflex to all necessary tests for a comprehensive clinical picture and patient specific diagnosis using 2008 WHO/REAL classification and 2008 NCCN guidelines
• Molecular analyses by the first commercial lab to bring you MPL and quantitative JAK2
• Morphology by a highly trained hematopathologist
• Multi-color flow cytometry by a team with over 100 years combined experience
• Cytogenetics/FISH with a high metaphase culture success rate

One hematopathologist is responsible for your case, from start to finish.
Contact your Genoptix Oncology Specialist at 800.755.1605 to learn more about our personalized diagnostic services.

Click here to view the MPD/MPN Case Study Review