The cobas 4800 BRAF V600 Mutation Test is a real-time PCR assay intended for the qualitative detection of the BRAF V600E mutation in DNA extracted from formalin fixed, paraffin-embedded human tumor tissue.

HER2 protein is detected by a primary monoclonal rabbit anti-human HER2 antibody (clone 4B5). HER2 expression level is determined by the staining pattern and percentage of invasive tumor cells, and is interpreted in accordance with CAP/ASCO Guidelines.

PR protein is detected by a primary monoclonal rabbit anti-human PR antibody (clone 1E2). PR status is determined determined by the intensity and percentage of appropriately stained tumor cells, and is interpreted in accordance with CAP/ASCO Guidelines.

ER protein is detected by a primary monoclonal rabbit anti-human ER antibody (clone SP1). ER status is determined determined by the intensity and percentage of appropriately stained tumor cells, and is interpreted in accordance with CAP/ASCO Guidelines.

Genoptix offers a comprehensive catalog of over 200 high-quality IHC antibodies and stains including stains for leukemia, lymphoma, breast cancer, prostate cancer, and more. You can easily pick and choose from our full menu–available in both global (with interpretation) or tech-only (no interpretation) options. When you order as tech-only, you’ll receive your digital slide images within one business day. Then, simply analyze and interpret the results. With the Genoptix Report Builder tool, you can easily review digital slide images and build a customized professional report. Don’t have time? Convert your case to global, and one of our expert pathologists will perform the interpretation for you.

Download our list of IHC stains

Genoptix offers pathologists an advanced tool to assess breast cancer biomarker status of Estrogen Receptor (ER), Progesterone Receptor (PR), HER2, and Ki-67. This imaging-based platform enables you to assess digital whole slide images, perform algorithmic calculations, and determine biomarker status via our easy-to-use, yet secure Report Builder™ website. By collaborating with Genoptix, you can work with a premier provider of Image Analysis by immunohistochemistry (IHC) technology using high quality standards and processes. The Genoptix Report Builder enables you to easily review digital slide images, score regions of interest, and build a customized professional report.

Rearrangement of the ROS1 gene is detected by fluorescence in situ hybridization (FISH).

Rearrangement of the RET gene is detected by fluorescence in situ hybridization (FISH).

Amplification of the MET gene is detected by fluorescence in situ hybridization (FISH).

Amplification of the ibroblast growth factor receptor 1 (FGFR1) gene is detected by fluorescence in situ hybridization (FISH).