Hematologic Diseases

Available as an add-on with an Intelligent Flow Profile. Markers tested by flow cytometry include cKappa, cLambda, CD5, CD19, CD10, CD11c, CD19, and CD20.

disease state indication(s)
Mature B-cell neoplasms

clinical use
The B-Cell Clonality add-on by flow cytometry aids in the evaluation of a monoclonal B-cell population with equivocal, nonspecific or absent expression of surface light chains.

methodology/product platform
Flow cytometry

specimen type and requirements
Peripheral blood: 5-6 mL in sodium heparin (green-top) tube.EDTA also acceptable. Acid-citrate-dextrose (ACD) unacceptable.
Bone marrow: 2-3 mL in sodium heparin (green-top) tube.
Fresh, unfixed tissue: 0.2 cm minimum in RPMI
Fine needle aspirate (FNA): Equal parts RPMI and specimen
Note: Use refrigerated cold pack for transport. Make sure cold pack is not in direct contact with specimen.
DO NOT FREEZE. Transport to lab ASAP.

turnaround time
Tech-only (TC): 12-24 hours
Global (TC & PC): 24-48 hours

cpt code(s)
Additional 88185 (x3) when added to Intelligent Flow Profile

medicare moldx cpt code
Not applicable

regulatory classification
Laboratory developed test (LDT)

ordering option
Global (TC & PC) or Tech-only (TC)