Hematologic Diseases

Available in conjunction with, or after, a Diagnostic/Prognostic Profile result has been reported by Genoptix or client. Markers tested by flow cytometry include cLambda, cKappa, CD5, CD10, CD19, CD20, CD45 and CD103.

disease state indication(s)
Mature B-cell neoplasms

clinical use
The B-Cell Clonality add-on by flow cytometry aids in the evaluation of a monoclonal B-cell population with equivocal, nonspecific or absent expression of surface light chains.

methodology/product platform
Flow cytometry

specimen type and requirements
Peripheral blood: 5-6 mL in sodium heparin (green-top) tube. EDTA also acceptable. Acid-citrate-dextrose (ACD) unacceptable.
Bone marrow: 2-3 mL in sodium heparin (green-top) tube.
Fresh, unfixed tissue: 0.2 cm minimum in RPMI
Fine needle aspirate (FNA): Equal parts RPMI and specimen
Note: Use refrigerated cold pack for transport. Make sure cold pack is not in direct contact with specimen.
DO NOT FREEZE. Transport to lab ASAP.

turnaround time
Tech-only (TC): 12-24 hours
Global (TC & PC): 24-48 hours

cpt code(s)
88184 (x1)
88185 (x7)
OR
Additional 88185 (x3) when added to immunophenotyping profile

medicare moldx cpt code
Not applicable

regulatory classification
Laboratory developed test (LDT)

ordering option
Global (TC & PC) or Tech-only (TC)