Hematologic Diseases

Available as a global test only. Markers tested by flow cytometry include  CD123, CD45, CD19, CD34, CD38, CD10, CD22, CD58, CD66C, CD9, CD13, CD33, and CD20.

disease state indication(s)
B-cell acute lymphoblastic leukemia (ALL)

clinical use
The B-ALL MRD Profile by flow cytometry evaluates for the presence of minimal residual disease (MRD) in patients with previously diagnosed and treated B-cell lymphoblastic leukemia (ALL). The limit of detection is 0.01%.

methodology/product platform
Flow cytometry

specimen type and requirements
Acceptable: Peripheral blood: 5-6 mL in sodium heparin (green-top) tube.
Bone marrow aspirate: 3 mL in sodium heparin (green-top) tube.
Unacceptable: Lithium heparin (red-top) tube.
Note: Use refrigerated cold pack for transport. Make sure cold pack is not in direct contact with specimen.

turnaround time
Global (TC & PC): 24-48 hours

cpt code(s)
88184 (x1)
88185 (x12)
88188 (x1)

medicare moldx cpt code
Not applicable

regulatory classification
Laboratory developed test (LDT)

ordering option
Global (TC & PC)