Hematologic Diseases

A tech-only 24-marker screening profile for bone marrow specimens. An evaluation of specimen adequacy and cellular integrity will also be performed. Markers include CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD11b, CD13, CD14, CD16, CD19, CD20, CD33, CD34, CD38, CD45, CD56, CD57, CD64, CD117, HLADR, Kappa and Lambda.

disease state indication(s)
Various, case dependent

clinical use
Comprehensive multiparameter flow cytometric analysis to assess various hematological cell subsets.

methodology/product platform
Flow cytometry

specimen type and requirements
Preferred:
Bone marrow aspirate: 2-3 mL in sodium heparin (green-top) tube.
Bone marrow core: 1-2 cm minimum core length in RPMI.

Acceptable alternative (Subject to viability):
Fluids: Equal parts RPMI and specimen

Use refrigerated cold pack for transport. Make sure cold pack is not in direct contact with specimen.
DO NOT FREEZE. Transport to lab ASAP.

turnaround time
Tech-only (TC): 12-24 hours

cpt code(s)
88184 (x1)
88185 (x23)

medicare moldx cpt code
Not applicable

regulatory classification
Laboratory developed test (LDT)

ordering option
Tech-only (TC)