Hematologic Diseases

Available as a global test only. Markers tested by flow cytometry include CD235a, CD15, CD64 and CD45; and antibodies to GPI-linked antigens CD14 (monocytes), CD24 (granulocytes) and CD59 (erythrocytes) and FLAER (monocytes and granulocytes).

disease state indication(s)
Paroxysmal nocturnal hemoglobinuria (PNH)

clinical use
High Sensitivity PNH Flow Cytometry aids in the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) and monitoring of treatment response. The limit of detection is 0.01% for RBC and 0.1% or better for WBC.

methodology/product platform
Flow cytometry

specimen type and requirements
Preferred: Peripheral blood: 5-6 mL in EDTA (purple-top) tube. Sodium heparin (green-top) tube is also acceptable.
Note: Use refrigerated cold pack for transport. Make sure cold pack is not in direct contact with specimen.
DO NOT FREEZE. Transport to lab ASAP.

turnaround time
Global (TC & PC): 24-48 hours

cpt code(s)
88184 (x1)
88185 (x7)
88187 (x1)

medicare moldx cpt code
Not applicable

regulatory classification
Laboratory developed test (LDT)

ordering option
Global (TC & PC)