Polymerase chain reaction (PCR) allows discrimination of individual members of the sufficiently diverse TCR-beta gene family. By using PCR amplification of the TCR-beta gene, a dominant clone can be identified in the majority of T-cell neoplasms.
disease state indication(s)
T-cell receptor (TCR) beta gene rearrangement analysis is useful for determining clonality in the diagnostic evaluation of T-cell neoplasms.
Polymerase chain reaction (PCR)
specimen type and requirements
Peripheral blood: 2-3 mL in EDTA (purple-top) tube.
Bone marrow: 2-3 mL in EDTA (purple-top) tube.
Note: Use refrigerated cold pack for transport. Make sure cold pack is not in direct contact with specimen.
DO NOT FREEZE.
Global (TC & PC): 7 days
medicare moldx cpt code
Laboratory developed test (LDT)
Global (TC & PC)